EntreChem SL is the only biotechnology company in the world using synthetic biology to develop hybrid natural products close to clinical trials.

A biotech company focused on optimizing natural anticancer products

EntreChem expertise on synthetic biology enables development of a pipeline of drugs for oncology approaching clinical trials.

EntreChem brings value to the natural products field by developing complex molecules not accessible using synthetic chemistry.

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Hybrid natural products close to clinical trials


Taking full advantage of our solid experience has enabled the advancement of our drug pipeline.

EntreChem’s promise: synergic poly-pharmacology in a single drug, a solution to overcome current treatment limitations.

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How we fight Ewing sarcoma?


A well-founded opportunity to treat pediatric and rare cancers.

EC-8042 – first in class transcriptional reprogramming agent for tumors with deregulated transcription.

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What are the benefits of multi-kinase inhibition?


Fighting Acute Myeloid Leukemia with a next-generation kinase inhibitor.

EC-70124 – a novel and superior triple FLT3-PIM-SYK inhibitor for the treatment of AML.

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How do we make drugs?


Engineering nature to fight cancer

Chemical space of selected natural products is expanded in order to de-toxify and improve the efficacy of anticancer molecules of natural origin.

EntreChem is a world-leader in advanced synthetic biology tools allow to increase the reach of combinatorial biosynthesis.

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Worlwide community of collaborators


EntreChem participates successfully in Spanish and International projects to fuel development of new technology and products.

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Excellent research, positive results


Selected outcomes of our internal and collaborative endeavors are published regularly in high impact journals.

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Meet us at…

Pamplona, SPAIN
Sept 29th – Oct 1st, 2021

Hamburg, GERMANY
November, 11-13th, 2019

October, 24-26th, 2019
Gobierno del Principado de Asturias
Innovative SMI