Updated list of our synthetic biology publications…
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- Genetic Engineering in Combination with Semi-Synthesis Leads to a New Route for Gram-Scale Production of the Immunosuppressive Natural Product Brasilicardin A
- Botas A, Eitel M, Schwarz PN, Buchmann A, Costales P, Núñez LE, Cortés J, Morís F, Krawiec M, Wolański M, Gust B, Rodriguez M, Fischer WN, Jandeleit B, Zakrzewska-Czerwińska J, Wohlleben W, Stegmann E, Koch P, Méndez C, Gross H.
- Angew Chem Int Ed Engl. 2021 Jun 7;60(24):13536-13541. doi: 10.1002/anie.202015852. PMID: 33768597
8
- An efficient blue-white screening system for markerless deletions and stable integrations in Streptomyces chromosomes based on the blue pigment indigoidine biosynthetic genebpsA
- Rezuchova B, Homerova D, Sevcikova B, Núñez LE, Novakova R, Feckova L, Skultety L, Cortés J, Kormanec J.
- Appl Microbiol Biotechnol. 2018 Sep 26. doi: 10.1007/s00253-018-9393-7 PMID: 30259098
7
- New Insights into the Biosynthesis Pathway of Polyketide Alkaloid Argimycins P in Streptomyces argillaceus
- Ye S, Braña AF, González-Sabín J, Morís F, Olano C, Salas JA, Méndez C.
- Front Microbiol. 2018 doi: 10.3389/fmicb.2018.00252 PMID: 29503641
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- Increased heterologous production of the antitumoral polyketide mithramycin A by engineered Streptomyces lividans TK24 strains
- Novakova R, Núñez LE, Homerova D, Knirschova R, Feckova L, Rezuchova B, Sevcikova B, Menéndez N, Morís F, Cortés J, Kormanec J.
- App. Microbiol. Biotechnol., 2018, 857-869. doi:10.1007/s00253-017-8642-5 PMID: 29196786
5
- Identification by Genome Mining of a Type I Polyketide Gene Cluster from Streptomyces argillaceus Involved in the Biosynthesis of Pyridine and Piperidine Alkaloids Argimycins P
- Ye S, Molloy B, Braña AF, Zabala D, Olano C, Cortés J, Morís F, Salas JA, Méndez C.
- Front Microbiol. 2017; 8: 194. doi:10.3389/fmicb.2017.00194 PMID: 28239372
4
- High-Quality Draft Genome Sequence of the Actinobacterium Nocardia terpenica IFM 0406, Producer of the Immunosuppressant Brasilicardins, Using Illumina and PacBio Technologies
- Buchmann A, Eitel M, Koch P, Schwarz PN, Stegmann E, Wohlleben W, Wolański M, Krawiec M, Zakrzewska-Czerwińska J, Méndez C, Botas A, Núñez LE, Morís F, Cortés J, Gross H.
- Genome Announcements 2016, 4 (6), e01391-16. doi:10.1128/genomeA.01391-16 PMID: 27979943
3
- Generation by mutasynthesis of potential neuroprotectant derivatives of the bipyridyl collismycin A
- Sialer C, García I, González-Sabín J, Braña AF, Méndez C, Morís F, Salas JA.
- Bioorg. Med. Chem. Lett. 2013 Oct 15;23(20):5707-9. doi:10.1016/j.bmcl.2013.08.017. PMID: 23993774
2
- Engineering the biosynthesis of the polyketide-nonribosomal peptide collismycin A for generation of analogs with neuroprotective activity
- García I, Vior NM, González-Sabín J, Braña AF, Rohr J, Morís F, Méndez C, Salas JA.
- Chem. Biol. 2013 Aug 22;20(8):1022-32. doi: 10.1016/j.chembiol.2013.06.014. PMID: 23911584
1
- Elucidating the biosynthetic pathway for the polyketide-nonribosomal peptide collismycin A: mechanism for formation of the 2,2′-bipyridyl ring-
- García I, Vior NM, Braña AF, González-Sabín J, Rohr J, Morís F, Méndez C, Salas JA.
- Chem. Biol. 2012 Mar 23;19(3):399-413. doi: 10.1016/j.chembiol.2012.01.014. PMID: 22444595
